Six disciplines. One continuous chemistry partner.
From the first retrosynthetic sketch to validated commercial batches, ART Biochem's capabilities are designed to work together, so your program never has to change hands.
Where we specialize
Each capability below can stand alone as a project scope, or combine into a single, seamless engagement.
API Intermediates
High-purity building blocks for complex formulations.
Fine & Specialty Chemicals
Custom routes for demanding, low-volume chemistry.
Amino Acids & It's Derivatives
Natural, non-natural & protected amino acids for pharmaceutical synthesis.
Custom Synthesis
Bespoke molecules built to your exact specification.
FTE Services
Dedicated scientific teams as an extension of your R&D.
CDMO Scale-Up
Seamless lab-to-plant technology transfer.
The critical building blocks, engineered right
We manufacture API intermediates with rigorous purity & quality control designed to meet the stringent safety & efficacy standards required by global regulatory bodies, from early development quantities to multi-tonne commercial supply.
- ✓ Impurity profiling & control strategy from kilo-lab stage
- ✓ Robust, reproducible processes ready for regulatory filing
- ✓ Flexible batch sizes from grams to metric tonnes
High-purity API intermediates
The routes larger manufacturers reject
We take on challenging, highly specialized synthetic routes, from complex molecular development to premium-grade fine chemicals, delivering custom solutions optimized for both pharmaceutical & advanced biotech applications.
- ✓ Multi-step synthesis with unstable or reactive intermediates
- ✓ Low-volume, high-value specialty compound manufacturing
- ✓ Route scouting for molecules with no established synthesis
Specialty synthesis
Amino acid chemistry, made reliable
We manufacture natural & non-natural amino acids & their derivatives, from protected building blocks to chirally pure specialty analogs. With end-to-end synthesis, precise molecular modification, & scalable production, we are a trusted partner for next-generation drug discovery.
- ✓ Protected amino acids: Fmoc, Boc, Cbz & ester derivatives
- ✓ Non-natural, N-methylated & unusual amino acids with controlled chirality
- ✓ Scale-up from milligram discovery to kilogram supply
Amino acids & derivatives
Built exactly to your specification
Whether it's a novel scaffold for a discovery program or a hard-to-source reference standard, our custom synthesis team designs & executes routes tailored precisely to your target molecule, timeline, & quantity requirements.
- ✓ Milligram to multi-kilogram custom quantities
- ✓ Confidentiality & IP protection built into every engagement
- ✓ Full characterization data package on delivery
Custom synthesis
Engineering the route for scale
Our process chemists re-engineer bench routes for safety, yield, cost, & reproducibility, closing the gap between "it works in the lab" & "it works in the plant" before a single kilo-lab batch is run.
- ✓ Design of Experiments (DoE) for critical process parameters
- ✓ Solvent, catalyst, & reagent optimization for cost & safety
- ✓ Hazard & thermal-stability assessment ahead of scale-up
Process development
Data you can file with
Method development, validation, & impurity profiling run in parallel with synthesis, not after it, so every batch arrives with the analytical package regulators expect to see.
- ✓ HPLC, GC, LC-MS, & NMR method development
- ✓ Stability studies & forced-degradation profiling
- ✓ Full validation packages aligned to ICH guidelines
Analytical development
CRO / CRAMS
Contract research & manufacturing support for programs that need scientific depth without building in-house infrastructure, spanning discovery synthesis through pilot-scale manufacturing.
Agile FTE Services
Instead of rigid contract structures, our FTE model gives your organization dedicated, highly skilled scientific teams acting as a seamless extension of your own R&D department, for rapid adaptability & focused problem-solving.
Bridging bench & plant
We bridge the gap between bench & plant. Our CDMO capabilities provide a seamless transition from lab-scale process development & analytical validation to highly efficient, scalable commercial manufacturing, without the bureaucratic delays of larger firms.
CDMO scale-up
Compliance built into the workflow, not bolted on
Innovation means nothing without compliance. We integrate comprehensive analytical testing, impurity profiling, & global regulatory compliance assistance directly into our workflow, ensuring your products are ready for successful international filings.
How a capability engagement typically runs
Scope & NDA
Define target, timeline, quantity
Feasibility
Route design & risk assessment
Development
Bench & kilo-lab execution
Scale-Up
Process & analytical validation
Delivery
cGMP batch & documentation